Neutron Crystallography, Molecular Dynamics, and Quantum Mechanics Studies of the Nature of Hydrogen Bonding in Cellulose Iβ. Nishiyama,Y., Johnson,G.P., French, A.D., Forsyth, V.T., Langan, P., Biomacromolecules (2008) [DOI: 10.1021/bm800726v].

Matchout deuterium labelling of proteins for low resolution neutron scattering studies of biological macromolecules, P. Callow, J.-B. Artero, M. Weidenhaupt, M. Smolle, O. Byron, J. G. Lindsay, S.C.M. Teixeira, M. Moulin, M. Haertlein, V.T. Forsyth, E. Biophys. J. (in preparation).

Selective deuteration of tryptophan and methionine residues in maltose binding protein: a model system for neutron scattering, Laux, V., Callow, P., Svergun, D.I., Timmins, P.A., Forsyth, V.T., Haertlein, M., Eur. Biophys. J. (2008) [DOI 10.1007/s00249-008-0280-5].

HsdR Subunit of the Type I Restriction-Modification Enzyme EcoR124I: Biophysical Characterisation and Structural Modelling, A. Obarska-Kosinska1, J.E. Taylor, P. Callow, J. Orlowski, J.M. Bujnicki, G.Kneale, J. Mol. Biol. 376, 438-452 (2008).

Selective deuterium labelling of DNA polymers, I. Parrot, M. Haertlein, V.T. Forsyth, E. Biophys. J. (in preparation).

New sources and instrumentation for neutrons in biology, S.C.M. Teixeira, G. Zaccai, J. Ankner, M.C. Bellissent-Funel, R. Bewley, M.P. Blakeley, P. Callow, L. Coates, R. Dahint, R. Dalgliesh, N.A. Dencher, V.T. Forsyth, G. Fragneto, B. Frick, R. Gilles, T. Gutberlet, M. Haertlein, T. Hauß, W. Häußler, W.T. Heller, et al., Chem. Phys. 345, 133-151 (2008)

In vivo measurement of internal and global macromolecular motions in E. coli, Jasnin M, Moulin M, Haertlein M, Zaccai G, Tehei M, In vivo measurement of internal and global macromolecular motions in E. coli , Biophys J. (2008) [doi:10.1529/biophysj.107.124420]

Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase, M.P. Blakeley, F.Ruiz, R. Cachau, I. Hazemann, F. Meilleur, A. Mitschler, S. Ginell, P. Afonine, O.N. Ventura, A. Cousido-Siah, M. Haertlein, A. Joachimiak, D. Myles, and A. Podjarny, Proc. Nat. Acad. Sci. USA 105, 1844-1848 (2008) [10.1073/pnas.0711659105].

A preliminary neutron crystallographic study of thaumatin, S.C.M. Teixeira, M.P. Blakeley, R.M.F. Leal, E.P. Mitchell and V.T. Forsyth, Acta Cryst. F64, 378-381 (2008) [doi:10.1107/S1744309108008294].

Complementing structural information of modular proteins with small angle neutron scattering and contrast variation, J.G. Grossmann, A.J. Callaghan, M. J. Marcaida, B.F. Luisi, F.H. Alcock, K. Tokatlidis, P. Timmins, M. Haertlein, Eur. Biophys. J. 37, 603-611 (2008).

Solvent isotope effect on macromolecular dynamics in E. coli, Jasnin M, Tehei M, Moulin M, Haertlein M, Zaccai G., Eur. Biophys. J. 37, 613-617 (2008).

X-ray and Neutron Small-Angle Scattering Analysis of the Complex Formed by the Met Receptor and the Listeria monocytogenes Invasion Protein InlB, Niemann HH, Petoukhov MV, Härtlein M, Moulin M, Gherardi E, Timmins P, Heinz DW, Svergun DI., J. Mol. Biol. 377, 489-500 (2008).

Coincidence of Dynamical Transitions in a Soluble Protein and Its Hydration Water: Direct Measurements by Neutron Scattering and MD Simulations, Wood K, Froelich A, Paciaroni A, Moulin M, Haertlein M, Zaccai G, Tobias GJ, Weik M, J. Am. Chem. Soc. 130, 4586-4587 (2008).

Down to atomic scale intracellular water dynamics, Jasnin M, Moulin M, Haertlein M, Zaccai G, Tehei M, EMBO Reports 9, 545-547 (2008).

Coupling of protein and hydration water dynamics in biological membranes, Wood, K., Plazanet, M., Kessler, B., Gabel, F., Oesterhelt, D., Tobias, D., Zaccai, G. & Weik, M., Proc. Natl. Acad. Sci. USA 104, 18049-18054 (2007) [DOI pnas.0706566104].

Expression, purification, assay, and crystal structure of perdeuterated human arginase, Di Costanzo L, Moulin M, Haertlein M, Meilleur F, Christianson DW, Arch Biochem Biophys 465, 82-9 (2007).

NMR Crystallography: The effect of deuteration on high resolution 13C solid state NMR spectra of a 7-TM protein, K. Varga, L. Aslimovska, I.M. Parrot, M.-T. Dauvergne, M. Haertlein, V.T. Forsyth, A. Watts, Biochim. Biophys. Acta. 1768, 3029-3035 (2007).

Adaptation to high temperatures through macromolecular dynamics by neutron scattering, Tehei, M., and Zaccai, G., FEBS Journal 274, 4034–4043 (2007).

Shape and subunit organisation of the DNA methyltransferase M.Ahdl, Callow, P., Sukhodub, A., Taylor, J., Kneale, G., J. Mol. Biol. 69, 177-185 (2007).

A methodology and an instrument for the temperature-controlled optimization of crystal growth, Budayova-Spano, M. , Dauvergne,F., Audiffren, M., Bactivelane, T., Cusack, S., Acta Cryst. D63, 339–347 (2007).

Neutron scattering reveals extremely slow cell water in a Dead Sea organism, M. Tehei, B. Franzetti, K. Wood,, F. Gabel, E. Fabiani, M. Jasnin, M. Zamponi, D. Oesterhelt, G. Zaccai, Margaret Ginzburg, and B.-Z. Ginzburg, Proc. Nat. Acad. Sci. USA, 104 (3), 766-771 (2007) [DOI pnas.0601639104].

Conformational Heterogeneity in RNA Polymerase observed by Single Pair FRET Microscopy, Coban, O., Lamb, D.C., Zaychikov, E., Heumann, H., Nienhaus, G.U., Biophys. J. 90, 4605-17 (2006).

X-rays and neutrons for the study of DNA structure, transitions and hydration, Parrot, I.M., Laux, V., Urban, V., Haertlein, M., Forsyth, V.T., Physica B, 385-386, 848 (2006).

Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase-inhibitor complex, Blakeley, M., et al, Eur. Biophys. J. 35 (7) (2006).

Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II, Budayova-Spano, M., et al, Acta Cryst. F62, 6-9 (2006)

High-Angle Neutron Fibre Diffraction in the Study of Biological systems, Forsyth, V.T., and Parrot, I.M., in Neutron Scattering in Biology - Techniques and Applications, Springer Series on Biological and Medical Physics/Biomedical Engineering) (2006), Eds Fitter, J., Gutberlet, T., Katsaras, J.

A preliminary neutron diffraction study of rasburicase, a recombinant urate oxidase enzyme, Budayova-Spano, M., et al, Acta Cryst. F62, 306-9 (2006).

The Subunit Arrangement of the Type I Restriction-Modification Enzyme M.AhdI, Callow, P., Timmins, P.A., Kneale, G., Physica B 385-386, 853 (2006).

Structural studies on acridine derivatives binding to telomeric DNA, Miles, S., Callow, P., Teixeira, S.C.T., Gan, Y., Denny, W., Cardin, C., Forsyth, V.T., Physica B 385-386, 845 (2006).

Disclosure of a communication route in the chaperonin GroEL: New structural insights into the allosteric mechanism, Bartolucci, C., Saulius Grazulis,S., Lamba, D., Manakova, E., Heumann, H., J. Mol. Biol. 354(4):940-51(2005).

A comparison of refined X-ray structures of hydrogenated and perdeuterated ray gamma E crystallin in H2O and D2O, Artero, J.B., Hartlein, M., McSweeny, S., Timmins, P.A., Acta Crystallographica D61, 1541-1549 (2005).

Combined X-ray and Neutron Fibre Diffraction Studies of Biological and Synthetic Polymers, Parrot, I.M., Urban, V., Gardner, K.H., Forsyth, V.T., Nucl. Instr. and Meth. in Phys. Res., B238, 7-15 (2005).

Neutron scattering reveals the dynamic basis of protein adaptation to extreme temperature, Tehei, M., Madern, D., Franzetti, B., Zaccai, J., J Biol Chem. 9, 280(49), 40974-9 (2005).

Etudes par diffraction de fibres de l’ADN double brin, Forsyth, V.T. and Parrot, I.M., Journal de Physique IV 130, 63-74 (2005).

Liquid-like water confined in stacks of biological membranes at 200 k and its relation to protein dynamics, Weik, M., Lehnert, U. & Zaccai, G., Biophys J., Biophys J., 89(5), 3639-46 (2005).

Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study, Gabel, F., Weik, M., Masson, P., Renault, F., Fournier, D., Brochier, L., Doctor, B., Saxena, A., Silman, I. & Zaccai, G., Biophys J., 89(5), 3303-11 (2005).

Real time characterization of intermediates in the pathway to open complex formation by RNA polymerase, Sclavi, B., Zaychikov, E., Rogozina, A., Walther, F., Buckle, M., Heumann, H., Proc. Natl. Acad. Sci. 102, 4706-4711 (2005)

High-resolution neutron protein crystallography with radically small crystal volumes: application of perdeuteration to human aldose reductase, Hazemann I, Dauvergne MT, Blakeley MP, Meilleur F, Haertlein M, Van Dorsselaer A, Mitschler A, Myles DA, Podjarny A., Acta Cryst. D61(10),1413-7 (2005).

Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam, Meilleur F, Dauvergne MT, Schlichting I, Myles DA, Acta Cryst. D61(5), 539-44 (2005).

Structural stability and dynamics of hydrogenated and perdeuterated cytochrome P450cam (CYP101), Meilleur F, Contzen J, Myles DA, Jung C., Biochemistry 13, 8744-53 (2004).

Water-DNA interactions by x-ray and neutron fibre diffraction, Fuller, W., Forsyth, V.T., Mahendrasingam, A., Phil. Trans. Roy. Soc., 359, 1448, 1237-1248 (2004).